Available without a prescription

At Border Compounding Pharmacy, we make a range of products that are available without a doctor’s prescription.
Click on the links below, then contact us to order or for more information.


Nausea and Vomiting During Pregnancy

During pregnancy, nausea and vomiting—also known as “morning sickness”—is a common problem… but it is a treatable one.

What causes it?

No one knows exactly why nausea and vomiting occur during pregnancy, but the symptoms are experienced by more than 85% of pregnant women. Most experience symptoms throughout the day (making the term “morning sickness” hardly accurate) and frequently these symptoms are worst in early pregnancy. Most women feel better by their fourth or fifth month—but for some, the symptoms can persist throughout their entire pregnancy.

The nausea and vomiting can be mild or severe, and in the worst cases it may even require hospitalisation due to dehydration and weight loss. The most severe form is called hyperemesis gravidarum, and this may affect up to 3% of pregnant women.

Regardless of its severity, such symptoms impact an expecting mother’s quality of life. Many women find they have to take time off work. Luckily, a range of treatment options are available that are safe for both mother and baby.

Approaches to treatment

As nausea and vomiting during pregnancy has no clear cause, treatments try to reduce the severity of the symptoms. The first approach is usually to change the diet (see below). If this does not help, a variety of over-the-counter and prescription treatments are available. Talk to your doctor before taking any over-the-counter or prescription medications while pregnant.

Dietary changes

  • Eat bland, dry foods that are high in carbohydrates or protein
  • Avoid strong flavours or odours.
  • As an an empty stomach can worsen symptoms, eat smaller, more frequent meals, before feeling hungry.
  • Some find relief from sipping cold fluids or sucking on ice chips.

Over-the-counter remedies 

These are safe treatments that may be useful for mild nausea and vomiting during pregnancy.

  • Ginger
  • Vitamin B6 (pyridoxine)
  • Acupressure (e.g., “travel sickness bands” or “sea bands”)

Prescription medications 

Many large studies have demonstrated a range of prescription medications to be safe and effective for the treatment of nausea and vomiting during pregnancy.

  • Doxylamine/pyridoxine combination (only available as a compounded preparation in Australia, see below)
  • Some antihistamines
  • Dopamine antagonists (e.g., metoclopramide or promethazine)

Doxylamine/pyridoxine combination 

This combination of an antihistamine and a vitamin B6 analogue is the first-line therapy for nausea and vomiting in pregnancy overseas. However, despite it being proven as the safest and most effective medicine it is not yet commercially available in Australia.

It is, however, available as a compounded preparation.

More information 

To learn more about the doxylamine/pyridoxine combination for managing nausea and vomiting in pregnancy, please contact one of our friendly pharmacists.


The BCP Custom Skincare system

BCP logo

BCP Custom Skincare is an easy four-step system to help you design a moisturiser that is best suited for your skin and needs.

Step 1: Choose your base consistency

To help you on your custom skincare journey, we have formulated four base moisturisers: three creams and a serum.

Our organic cream bases contain avocado oil, squalene and hyaluronate, a combination that is naturally rich in vitamins A and D, with anti-ageing properties. These bases are formulated to match the skin’s natural pH. They spread easily on the skin and penetrate deeply, keeping skin hydrated, elastic, soft and smooth.

We describe our bases by their skin-feel and emollience:

Emollient (adj): having the quality of softening or soothing the skin.

LIGHT Avocado Oil
Squalene
Hyaluronate
A light and non-greasy cream base that soothes and revives dry and tired skin.
Especially suitable for young skin and for application to the face.
MEDIUM Avocado Oil
Squalene
Hyaluronate
Shea Butter
A cream base made slightly more emollient by the addition of Shea butter (which adds antioxidants, omega-3, omega-6 and omega-9 fatty acids and vitamins).
Suitable for all skin types.
HEAVY Avocado Oil
Squalene
Hyaluronate
Shea Butter
Beeswax
Our most emollient cream base. The addition of beeswax makes this base deeply moisturising, as well as increasing the vitamin A content and imparting antibacterial and anti-inflammatory properties.
Very suitable for dry, aged or damaged skin.
SERUM (15ml only) Hyaluronate Our serum base is the lightest in consistency overall, yet still deeply hydrating. Useful as a simple base for the addition of specific vitamins and oils, such as those below.

Step 2: Choose your vitamins

You can add vitamins to help heal, protect, and hydrate your skin.

Coenzyme Q10 Potent antioxidant
Heals & repairs
Increases collagen production
May protect against damage from sun exposure
Reduces the appearance of skin wrinkles & age spots
Vitamin A Improves skin cell turnover
Stimulates new blood vessel formation
Promotes collagen remodelling
Reduces the visible signs of ageing
May reduce acne
Vitamin B3 Important for cellular metabolism
Essential for healthy skin
May reduce acne, rosacea & skin hyperpigmentation
Reduces the visible signs of ageing
Vitamin E Strong antioxidant
Protects skin cell membranes from damage
May assist with wound healing
Vitamin B5 Increases skin elasticity
Nurtures skin against itching, dryness, and irritation
Improves the appearance of age-related skin changes like wrinkles & spots
May improve wound healing
May reduce the visibility of old and new scars
Vitamin K Reduces dark circles under eyes
Assists with bruise healing
May reduce rosacea
Vitamin B12 Necessary for metabolism of fatty & amino acids
Important in DNA synthesis
May relieve eczema & psoriasis

Read more on our skincare vitamins and their effects.

Step 3: Choose your extra oils

You can add one or more of our range of specialist organic oils, to add emollience and skin-enhancing properties.

Almond Oil High levels of omega 6 & 9 fatty acids
Moisturises all skin types
Olive Oil High levels of omega 3 & 6 fatty acids
Suited to dry or mature skin
Soothes irritated skin
Lanolin oil Similar to the skin’s natural oils
High in moisturising alpha hydroxyl acids (AHA)
Very good for barrier creams
Rosehip Oil Rich in omega 3, 6 & 9 fatty acids and Vitamins A, E & C
Rich in lycopene & beta carotene
Powerful antioxidant properties
Nurtures skin regeneration
Improves the appearance of age-related skin changes (e.g. wrinkles & spots)
Coconut oil Antibacterial properties
Protects skin cells from damage
Deeply hydrating

Read more about the oils in our skincare products here.

Step 4: Choose your size

Our BCP Custom Skincare products are supplied in easy-to-use airless pump dispensers that keep the product fresh and free of contamination.

100ml pump $49
200ml pump $69
15ml pen (Serum only) $49

BCP Custom Skincare products should be stored in a cool place, protected from overly warm and humid conditions (such as that found in many bathroom areas).

Get yours today

Would you like to order a BCP Custom Skincare product? There are three easy ways to let us know how you would like your skincare.

Any questions? Why not contact our friendly professional staff, and let us help you.

Remember

BCP products are unique, because they are formulated by pharmacists.

We can include a range of fragrances, or you can leave them fragrance-free. Also, for those concerned about preservatives, we can make them preservative-free.

We also customise other skin and hair care products (e.g. cleansers, shampoos, or conditioners).

However you prefer your skincare, we have the expertise to prepare it—just for you!


Topical Vitamin B3

What is Vitamin B3?

Niacin or nicotinic acid and nicotinamide are both forms of Vitamin B3.

Nicotinamide

Nicotinamide

Nicotinamide (also known as niacinamide) is the active, water soluble form of vitamin B3, whereas nicotinic acid (also known as niacin) is converted into nicotinamide in the body (1). As vitamins, niacin and nicotinamide are identical. Their pharmacological effects, however, are considerably different. Unlike nicotinamide, niacin lowers cholesterol, causes vasodilation, skin flushing, headache, and hypotension.

Vitamin B3 serves as a precursor of several co-enzymes (facilitators of enzymatic reactions) essential for numerous metabolic pathways. These co-enzymes play a key role in the metabolism of glucose, cellular energy production, and synthesis of lipids.

So why put Vitamin B3 on the skin?

Different tissues have different thresholds for vitamin B3 deficiency, with the skin being highly susceptible (1). Nicotinamide applied topically has been shown in scientific studies to improve many skin conditions, including acne vulgaris, rosacea and melasma (hyperpigmentation) and atopic dermatitis (2).

As a skin treatment Vitamin B3 is well tolerated, and may be found acceptable by those who cannot tolerate other treatments (such as topical retinoids or fruit acids). However, it is not recommended for use by pregnant and nursing women.

Vitamin B3 for acne

Topical vitamin B3 has also been shown to be effective in the treatment of acne. A 4% or 5% nicotinamide gel has been found to be as effective as the topical antibiotic clindamycin in either a 1% or 2% gel in the treatment of acne vulgaris in patients with mild-moderate acne (3,4). The study concluded that the anti-inflammatory properties of nicotinamide may have contributed towards its success in acne.

Vitamin B3 has also been shown to reduce facial sebum production. Sebum is responsible for facial shine and contributes to non-inflamed comedones (small, skin-coloured bumps frequently found on the forehead and chin of those with acne) and inflammatory acne lesions. Application of a 2% nicotinamide moisturiser to the face for 4-6 weeks has been shown to reduce sebum production with significant differences in facial shine and oiliness (5).

Vitamin B3 for rosacea

The clinical signs and symptoms of rosacea include increased facial skin dryness, redness and sensitivity. Moisturisers containing nicotinamide have been shown to improve skin barrier function in rosacea patients, leading to diminished reaction to irritants including cleansers and cosmetics (6, 7).

Vitamin B3 for hyperpigmentation and melasma

Skin hyperpigmentation occurs in multiple conditions, and it can be particularly difficult to treat on darker skin. Melasma is a chronic skin disorder that results in symmetrical, blotchy, brownish facial pigmentation that can lead to considerable embarrassment and distress. Nicotinamide has been shown to be effective at reducing uneven pigmentation in these conditions (8, 9, 10).

Vitamin B3 for anti-ageing skin care

The levels of Vitamin B3-dependent coenzymes in the skin can decrease with age, and in several studies topical nicotinamide has appeared to reverse some of these declines. Several studies have shown that topical nicotinamide improved fine lines and wrinkles, hyperpigmented “age” spots, red blotchiness, and skin sallowness (yellowing) as well as elasticity (11). One study showed nicotinamide to increase the skin’s production of ceramides (natural emollients and skin protectants) and therefore improving skin hydration (12). Another study reported improvement of eyelid wrinkles after 8 weeks of application of a cosmetic containing 4% nicotinamide (13).

Our formulation

Available-without-a-prescriptionWe have formulated a BCP Vitamin B3 gel that is a 4% w/w nicotinamide gel in a non-comedogenic hyaluronate gel base. This gel can be made to any other strength as desired.

Our custom-made 4% Vitamin B3 in hyaluronate gel is available in 50 ml pump packs through our secure BCP Shop online, or by contacting us.

We recommend that Vitamin B3 gels be applied twice daily. If this application rate causes excessive skin drying, it may be applied once daily or every other day.

More information

When used to help with acne, it is worth considering that sometimes biofilms of acne-causing micro-organisms are present that may worsen the condition. Using a Vitamin B3 gel in combination with an EDTA-containing product like our BCP EDTA foaming wash may enhance each product’s benefits—with or without concurrent topical antibiotic preparation prescribed by your doctor.

For another way to incorporate Vitamin B3 into your skin care, please consider our BCP Custom Skincare options. We give you control of your skin care, so why not contact us with any requests?

Why not read more about the benefits of vitamins in skin care products?

BCP products are unique, because they are formulated by pharmacists.

References

  1. Rolfe HM (2014) A review of nicotinamide: treatment of skin diseases and potential side effects. J Cosmet Dermatol. 13(4): 324-8.
  2. Niren NM (2006) Pharmacologic doses of nicotinamide in the treatment of inflammatory skin conditions: a review. Cutis. 77(1 Suppl): 11-6.
  3. Khodaeiani E, et al. (2013) Topical 4% nicotinamide vs. 1% clindamycin in moderate inflammatory acne vulgaris. Int J Dermatol. 52(8): 999-1004.
  4. Shahmoradi Z, et. al. (2013) Comparison of topical 5% nicotinamid gel versus 2% clindamycin gel in the treatment of the mild-moderate acne vulgaris: A double-blinded randomized clinical trial. J Res Med Sci. 18(2): 115-7.
  5. Draelos ZD, et al. (2006) The effect of 2% niacinamide on facial sebum production. J Cosmet Laser Ther. 8(2): 96-101.
  6. Draelos ZD, et al. (2005) Niacinamide-containing facial moisturizer improves skin barrier and benefits subjects with rosacea. Cutis. 76(2): 135-41.
  7. Wozniacka A, et al. (2005) Topical application of 1-methylnicotinamide in the treatment of rosacea: a pilot study. Clin Exp Dermatol. 30(6): 632-5.
  8. Hakozaki T, et al (2002) The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer. Br J Dermatol. 147(1): 20-31.
  9. Navarrete-Solís J, et al. (2011) A Double-Blind, Randomized Clinical Trial of Niacinamide 4% versus Hydroquinone 4% in the Treatment of Melasma. Dermatol Res Pract. 2011: 379173.
  10. Rendon M and Horwitz S. (2012) Topical treatment of hyperpigmentation disorders. Ann Dermatol Venereol. 139 Suppl 4: S153-8.
  11. Bissett DL , et al. (2004) Topical niacinamide reduces yellowing, wrinkling, red blotchiness, and hyperpigmented spots in aging facial skin. Int J Cosmet Sci. 26(5): 231-8.
  12. Tanno O, etal. (2000) Nicotinamide increases biosynthesis of ceramides as well as other stratum corneum lipids to improve the epidermal permeability barrier. Br J Dermatol. 143(3): 524-31.
  13. Kawada A, et al. (2008) Evaluation of anti-wrinkle effects of a novel cosmetic containing niacinamide. J Dermatol. 35(10): 637-42.

Biofilms, skin disorders and EDTA

Staphylococcus aureus biofilm on a catheter.

Staphylococcus aureus biofilm on a catheter.

What are biofilms?

Biofilms are diverse communities of microorganisms (e.g. bacteria, fungi and yeasts) that embed themselves within a self-produced matrix and in doing so firmly attached themselves to one another and/or to surfaces. These surfaces may be biological (e.g. skin, wounds, teeth, or other body membranes), or not (e.g. implements, medical devices, furniture, or jewellery). The biofilm promotes the growth of the microorganisms, resulting in the thickening of the biofilm. In extreme cases, biofilms may appear as a “slime” to the naked eye.

Why are biofilms important?

Biofilms may harbour disease-causing organisms. According to one estimate, up to 80% of all microbial infections involve biofilm formation (1). If an infection develops a biofilm, it becomes even harder to treat. Biofilms are remarkably difficult to treat with antimicrobials, but the reasons for this are not clear.  Antimicrobials may be inactivated or may fail to penetrate into the biofilm.  In addition, bacteria within biofilms have increased (up to 1000-fold higher) resistance to antimicrobial compounds, and to the body’s defences (1, 2). Due to their embeddedness and resistance, biofilms often prove difficult to remove.

It has been suggested that skin biofilms may explain the chronic nature of many dermatological conditions, including atopic dermatitis, poor wound healing, acne, Candida infections, impetigo and boils (3).

The chelating agent, EDTA

EDTA

The chelating agent, EDTA

N,N’-ethylenediaminetetraacetic acid — or EDTA for short — is an agent that binds up metal ions in solution. Because it holds to metal ions so tightly, it is also able to pull them away from their functions in biological molecules. In biofilms, metal ions are thought to be required for the creation of the microbial matrix and/or the adhesion within it — and so removing them with EDTA destroys the biofilm’s integrity.

In scientific studies, EDTA has been shown to be effective at removing microorganisms from a range of medically-relevant biofilms (4, 5, 6). This action has led to it being used to reduce infection risk in medical applications such as dialysis and device implantation, some wound dressings, and in dentistry (7, 8, 9, 10, 11).

Skin care products containing EDTA

Available-without-a-prescriptionAsk us about the dermatological preparations in which we have formulated EDTA. These products include lotions, gels, and foaming skin-wash products. These products are typically used twice daily.

Such products may be especially useful when used in conjunction with other skin preparations. For example, they may be applied as a cleanser before topical antibiotics for acne therapy.

An EDTA-containing wash may also boost the action of our Vitamin B3-containing preparations in reducing biofilm-feeding sebum secretions, reducing inflammation, and promoting healing.

References

  1. “Research on microbial biofilms (PA-03-047)”. NIH, National Heart, Lung, and Blood Institute. 2002-12-20.
  2. Bryers, JD (2008) Medical biofilms. Biotechnology and Bioengineering, 100(1): 1-18.
  3. Nusbaum AG, et al. (2012) Biofilms in Dermatology. Skin Therapy Letters, 17(7):1. (http://www.skintherapyletter.com/2012/17.7/1.html)
  4. Raad I, et al. (2003) In Vitro and Ex Vivo Activities of Minocycline and EDTA against Microorganisms Embedded in Biofilm on Catheter Surfaces. Antimicrobial Agents and Chemotherapy 47(11): 3580–3585.
  5.  Banin E, et al. (2006) Chelator-Induced Dispersal and Killing of Pseudomonas aeruginosa Cells in a Biofilm. Appl Environ Microbiol. 72(3): 2064–2069.
  6. Robertson EJ, et al. (2012) EDTA Inhibits Biofilm Formation, Extracellular Vesicular Secretion, and Shedding of the Capsular Polysaccharide Glucuronoxylomannan by Cryptococcus neoformans. Appl. Environ. Microbiol. 78(22): 7977-7984
  7. Kadry AA, et al. (2009). Impact of slime dispersants and anti-adhesives on in vitro biofilm formation of Staphylococcus epidermidis on intraocular lenses and on antibiotic activities. Journal of Antimicrobial Chemotherapy. 63 (3): 480.
  8. Thomsen TR, et al. (2011) The role of bacterial biofilms in infections of catheters and shunts. In: Bjarnsholt Thomas., editor; , Jensen Peter Østrup., editor; Moser Claus., editor; , Høiby Niels., editor. , eds. Biofilm Infections. New York: Springer. pp 91–109.
  9. Stoodley P, et al. (2012) Biofilms, biomaterials, and device-related infections. In: Ratner BD, editor; , Hoffman AS, editor; , Schoen FJ, editor; , Lemons JE, editor. , eds. Biomaterials Science an Introduction to Materials in Medicine, 3rd ed. Oxford, UK: Elsevier, pp 565–583.
  10. Lambert RJW, et al. (2004) The synergistic effect of EDTA/antimicrobial combinations on Pseudomonas aeruginosa. J. Appl. Microbiol. 96:244–253.
  11. Finnegan S and Percival SL (2015) EDTA: An Antimicrobial and Antibiofilm Agent for Use in Wound Care. Adv Wound Care (New Rochelle). 4(7): 415–421.

Vitamin K for cosmetic laser recovery and bruising

Most people have heard of B-group vitamins and Vitamins C and E, but although Vitamin K is less well-known it is no less important. It has been shown to have some surprising properties when applied to the skin.

What is Vitamin K?

Phytomenadione, also known as Vitamin K1

Vitamin K1 (phytomenadione, or phylloquinone) is found in highest amounts in leafy green vegetables, because in plants it is directly involved in photosynthesis. It is a fat-soluble vitamin that is stored in the human body, and both deficiencies and excesses are rare in the absence of other pathologies.

As a vitamin, vitamin K has one main function: blood clotting. It is required for the liver to activate a group of proteins called coagulation factors, all of which are necessary for blood to clot. In fact, the “K” in its name comes from its name in German, “Koagulationsvitamin”. The commonly-prescribed anticoagulant medication warfarin works by antagonising (opposing) Vitamin K’s action.

Vitamin K also plays an important role in bone health.

So why put Vitamin K on the skin?

Bruising (or pupurea) is a common side-effect of many cosmetic laser treatments, for example laser hair removal or laser skin resurfacing. Several studies have found that products containing at least 1% w/w vitamin K shorten the length of time that skin is reddish-purple when these products are applied after laser treatment (2, 3, 4).

Vitamin K may also be applied to other skin areas that may benefit from bruise-reduction. For example, a cream containing 2% vitamin K, 0.1% retinol and 0.1% vitamins C and E has been shown to have a moderate effect on reducing dark circles under eyes (5).

Topical vitamin K has also been shown to promote the healing of wounds (6).

Topical application of vitamin K is unlikely to have any effect on systemic blood clotting, as it has no known toxicity in overdose. Any small amounts that may be absorbed across the skin must be significantly diluted before they can exert any effect where coagulation factors are activated in the liver.

Our products

Available-without-a-prescriptionBCP Vit K Serum

We have formulated a 2% w/w vitamin K serum that may be suitable for topical application after laser treatment or to other skin areas (e.g. for bruising, or for dark circles under eyes).

BCP CEK gel

Formulated specifically for use post-laser treatment, the BCP CEK Gel contains 2% w/w vitamin K in a regenerative, non-comedogenic hyaluronate gel base that also contains Ascorbic acid (Vitamin C) and vitamin E. This broad-spectrum antioxidant combination is designed to reduce the redness and bruising that may occur after cosmetic laser treatments. It is all-natural, and prepared to order.

More information

As with all of our products, we can custom-make your Vitamin K product to suit your skin type and requirements. If you have any questions or would like to make an order, please don’t hesitate to contact us.

References

    1. “Vitamin K Overview”. University of Maryland Medical Center. http://umm.edu/health/medical/altmed/supplement/vitamin-k (accessed 26 February 2016).
    2. Lou WW, et al. (1999) Effects of topical vitamin K and retinol on laser-induced purpura on nonlesional skin. Dermatologic Surgery 25(12):942-4.
    3. Shah NS, et al. (2002) The effects of topical vitamin K on bruising after laser treatment. J Am Acad Dermatol. 47(2):241-4.
    4. Cohen JL and Bhatia AC (2009) The role of topical vitamin K oxide gel in the resolution of postprocedural purpura. J Drugs Dermatol. 8(11):1020-4.
    5. Mitsuishi T, et al. (2004) The effects of topical application of phytonadione, retinol and vitamins C and E on infraorbital dark circles and wrinkles of the lower eyelids. J Cosmetic Dermatology. 3(2): 73-75
    6. Hemmati AA, et al. (2014) Topical vitamin K1 promotes repair of full thickness wound in rat. Indian J Pharmacol. 46(4):409-12.

Nutrigenomic and Neutraceutical Services

Are you always feeling tired and run down, and can’t understand why?

Or, do you suspect your health problems may be caused by some nutritional deficiency?

It is possible that you have a specific vitamin or mineral deficiency. Lifestyle (and particularly diet) and illness can play havoc with the nutrients your body needs for optimal health, but did you know that your genes may also play a role?

Not all equal

Your body is as entirely unique as your genetic make-up. Just as your genetics makes you look different from everyone else around you, it also influences the way that your body uptakes individual nutrients from the food you eat, and the way your body uses them. Genetic deficiencies occur when one or more of the body’s pathways for handling a nutrient (e.g. for its absorption from the gut, or for converting it from an inactive to an active form) does not function adequately.

In extreme cases of genetic deficiency, one may consume the correct amount of a specific nutrient—or even take a supplement—and not experience the health benefit of that nutrient.

For more information about some deficiencies, read our other posts about Key minerals and B group Vitamins, about how many Australians are deficient in Vitamin D, and about Folate deficiency and why folic acid supplements may NOT work.

Fortunately, a suite of tests are available to identify the causes of nutritional deficiencies. When a specific deficiency’s cause is known, it may be overcome by taking an appropriate supplement. Sometimes, no appropriate supplement is commercially available and can only be formulated in a compounding pharmacy.

What we offer

Available-without-a-prescriptionAt Border Compounding Pharmacy, we offer a comprehensive nutrigenomic and nutraceutical service that may include any or all of the following:

  • Pathology testing for nutritional deficiencies
  • Genetic testing for common nutritional processing defects
  • Formulation of custom nutritional supplements to suit your needs

Please contact us to arrange our services, or to learn more about how we can help you.


BCP Vitamin C Serum

10-20% Ascorbic acid, 1% Vitamin E, and 1% Ferulic acid in Hyaluronate gel

Why put Vitamin C on the skin?

When skin is exposed to sunlight—and particularly to the high-energy ultraviolet spectrum it contains—many chemical changes take place within its cells and proteins. A major mechanism by which these changes take place is known as photo-oxidation, a kind of damage caused by sunlight-induced free radicals (a kind of reactive, damaging chemical).

Antioxidants are so-called “scavengers” of free radicals, and they can be applied to the skin to prevent and treat damage. The safest antioxidants are those found in nature.

L-Ascorbic acid

L-Ascorbic acid

Vitamin C (or L-ascorbic acid) is a natural and potent antioxidant that can be used topically to treat and prevent changes associated with sun exposure and photo-ageing. It has also been used for the treatment of hyperpigmentation (e.g. melasma and “age” or “liver” spots) and scarring.

Unfortunately, because vitamin C is such a good antioxidant, it oxidises very quickly and inactivates. As a result, stable derivatives of vitamin C have been synthesized that allow it to be manufactured into products and warehoused for long periods of time. These derivatives of vitamin C may be found in some cosmetic products marketed as being lipid soluble, or as having enhanced skin penetration. However, the stability of these derived forms comes at the cost of their decreased effectiveness as antioxidants.

What is hyaluronate?

Hyaluronic acid is a major components of the dermis (the inner layer of the skin) and it plays a large role in skin regeneration and hydration. It can absorb phenomenal amounts of moisture—1 gram of hyaluronate can hold up to 6 litres of water—and this makes it a potent skin hydrator. Ageing and sun exposure both decrease the amount of hyaluronate in the skin.

Why not read more about why we choose hyaluronate for our products?

Our formulation

Available-without-a-prescriptionOur BCP Vitamin C Serum is formulated in a healing, non-comedogenic gel base of hyaluronate, for its regenerative properties and because such bases are suitable for ANY skin type (e.g. acne prone, oily, dry, sensitive or rosacea affected). We incorporate additional natural antioxidants, vitamin E and ferulic acid (an antioxidant found in many foods), to both improve the stability of Vitamin C and enhance the product’s overall beneficial effect.

At Border Compounding Pharmacy, we do not keep pre-made BCP Vitamin C Serum on the shelf. We prepare each batch fresh, to maximise the antioxidant power of vitamin C. We recommend storage in the refrigerator to maximise and maintain its effectiveness.

More information

We can design your BCP Vitamin C Serum specifically for your skin type and requirements. If you would like more information, or wish to a discuss a suitable strength, please don’t hesitate to contact us.


Motion Sickness Cream

motionsickness

Do you suffer from motion sickness when driving, flying or sailing? Many otherwise healthy people do, and often right in the middle of that long-awaited holiday or fishing trip.

It is a debilitating experience that can make a misery out of travel or recreational activities. Worse, most currently available treatments have the drawback of causing severe drowsiness and a dry mouth – side effects that are as unwanted as the motion sickness itself.

Our approach

Available-without-a-prescriptionOur over-the-counter product (i.e., it does not require a doctor’s prescription) is highly effective at preventing the nausea, dizziness and fatigue of this common ailment from occurring.

It is a specialised ‘transdermal’ cream containing active ingredients that are clinically proven to help with nausea and motion sickness. By delivering the drugs through the skin rather than through the gut, the stomach is bypassed, and the drugs enter the circulation more slowly and evenly over the space of the day.  This means that dosing is not as frequent, and less side effects occur.

It is formulated in a smooth, moisturising cream base that is easily-applied, non-comedogenic and free of parabens.

How to use our Motion Sickness Cream

The cream should be applied to a clean, dry, hairless area behind the ear. Application at least 4 hours before its effects is needed to allow the medication sufficient time to be absorbed across the skin and to become effective.

Are there any side effects?

The side effects of our Motion Sickness Cream should be minimal. If they occur at all they are usually limited to mild sedation (sleepiness or drowsiness) and a dry mouth — however unlike a tablet and because it is a cream, any side effects that do occur can be easily managed by simply applying less on the next application.

Ordering

To learn more about our motion sickness cream, simply contact us and one of our pharmacists will be happy to help.


Topical Oxymetazoline: A Novel Approach to Treat Rosacea

What is rosacea?rosacea on nose

Rosacea is a chronic skin complaint affecting the face. It is characterised by small dilated blood vessels and often includes small pustules and papules. Whilst the precise cause of rosacea is unknown, any activity causing facial flushing, such as temperature fluctuations, blushing, stress, sunburn, exercise, consuming caffeine and spicy food can contribute to its severity. In fact, the symptom of flushing is enough to potentially diagnose rosacea, and those who describe themselves as having ‘sensitive’ skin may be suffering mild rosacea. Traditional pharmaceutical approaches to rosacea include antibiotics, immune-suppressants and retinoids. However, another agent with apparently fewer potential side effects is gaining attention.

Oxymetazoline

Oxymetazoline is a vasoconstrictor which is commonly used in nasal sprays as a nasal decongestant. It works by causing the smooth muscle around blood vessels to contract, making the vessels smaller and less dilated. Thus it would appear to be a good candidate for treating rosacea.

Indeed, the Rosacea International Expert Group has noted that topical oxymetazoline has a role in the treatment of rosacea and the group recommends its use.
Studies have found that after applying oxymetazoline to the skin once a day, a decrease in redness was noted in 1 hour and the effect was sustained throughout the day. Continued application once a day over several months was associated with a marked improvement of rosacea symptoms. These results were sustained after prolonged use at 17 months.

Once a day treatment with an oxymetazoline cream markedly improves rosacea symptoms, long term.

When compared to the other agents currently used, oxymetazoline presents fewer issues with potential side effects and its application results in a rapid improvement of symptoms.

More information

Oxymetazoline may be compounded into a range of rosacea-friendly topical bases (e.g. gels and facial creams). Please contact us if you would like more information on oxymetazoline products, or if you think it might be suitable for you.

Also, consider topical Vitamin B3 (nicotinamide) for the treatment of rosacea, possibly in combination with oxymetazoline. Vitamin B3 has also been shown to both improve rosacea symptoms and prevent recurrences, is all-natural and has a very low potential for side effects.


Treating Eczema with Topical Vitamin B12

For the treatment of eczema in both adults and children, topical Vitamin B12 is superior to emollients or moisturisers, and safer than steroid creams.

Image by James Heilman, MD - Own work, CC BY-SA 4.0, https://commons.wikimedia.org/w/index.php?curid=40647837

A moderate case of dermatitis of the hands.

Eczema

Eczema, also known as dermatitis, is a chronic condition in which patches of skin become rough and inflamed with blisters which cause itching and bleeding. It may effect both adults and children.

Generally speaking, treatment guidelines for eczema involve:

  1. Emollients or moisturisers when the condition is mild; and
  2. Steroid creams when the condition is more aggravated.

The problem with moisturisers is that they are often not sufficient to prevent the eczema from flaring up, and the problem with steroid creams is that they have a large array of potential side effects.

Vitamin B12 as an all-natural treatment for eczema

Studies have shown that topical vitamin B12 can successfully treat dermatitis in both adults and children.  It is theorised that vitamin B12 causes a decrease in the production of nitric oxide—a pro-inflammatory chemical—in the middle layer of the skin, the dermis.  In one randomised, double-blind, placebo controlled multi-centre clinical trial presented in the British Journal of Dermatology, the results documented: “a significant superiority of vitamin B12 cream in comparison with placebo with regard to the reduction of the extent and severity of atopic dermatitis”. It also demonstrated “a continuously progressive beneficial treatment effect throughout the 8 week treatment phase. It can therefore be postulated that treatment beyond 8 weeks would result in further alleviation of signs to the point of complete remission.” (British Journal of Dermatology 2004; 150: 977-983).

Considering the almost non-existent potential for any side effects, topical vitamin B12 is undeniably a product of choice for the treatment of eczema in both adults and children alike.

Our formulation

Available-without-a-prescriptionWe have formulated a unique formula, containing only natural ingredients including squalene, avocado oil and Vitamin B12 (cyanocobalamin).  It has been formulated to be intensely hydrating without leaving the skin oily.

BCP Vitamin B12 cream               $49 – 100ml                 $69 – 200ml

As with all of our products, we are able to formulate the cream according to your specifications should you have any problems with the listed ingredients.

BCP Vitamin B12 cream is available to purchase securely online through our BCP shop.

More information

Please contact us with any questions that you may have.