Compounding & formulation


Nausea and Vomiting During Pregnancy

During pregnancy, nausea and vomiting—also known as “morning sickness”—is a common problem… but it is a treatable one.

What causes it?

No one knows exactly why nausea and vomiting occur during pregnancy, but the symptoms are experienced by more than 85% of pregnant women. Most experience symptoms throughout the day (making the term “morning sickness” hardly accurate) and frequently these symptoms are worst in early pregnancy. Most women feel better by their fourth or fifth month—but for some, the symptoms can persist throughout their entire pregnancy.

The nausea and vomiting can be mild or severe, and in the worst cases it may even require hospitalisation due to dehydration and weight loss. The most severe form is called hyperemesis gravidarum, and this may affect up to 3% of pregnant women.

Regardless of its severity, such symptoms impact an expecting mother’s quality of life. Many women find they have to take time off work. Luckily, a range of treatment options are available that are safe for both mother and baby.

Approaches to treatment

As nausea and vomiting during pregnancy has no clear cause, treatments try to reduce the severity of the symptoms. The first approach is usually to change the diet (see below). If this does not help, a variety of over-the-counter and prescription treatments are available. Talk to your doctor before taking any over-the-counter or prescription medications while pregnant.

Dietary changes

  • Eat bland, dry foods that are high in carbohydrates or protein
  • Avoid strong flavours or odours.
  • As an an empty stomach can worsen symptoms, eat smaller, more frequent meals, before feeling hungry.
  • Some find relief from sipping cold fluids or sucking on ice chips.

Over-the-counter remedies 

These are safe treatments that may be useful for mild nausea and vomiting during pregnancy.

  • Ginger
  • Vitamin B6 (pyridoxine)
  • Acupressure (e.g., “travel sickness bands” or “sea bands”)

Prescription medications 

Many large studies have demonstrated a range of prescription medications to be safe and effective for the treatment of nausea and vomiting during pregnancy.

  • Doxylamine/pyridoxine combination (only available as a compounded preparation in Australia, see below)
  • Some antihistamines
  • Dopamine antagonists (e.g., metoclopramide or promethazine)

Doxylamine/pyridoxine combination 

This combination of an antihistamine and a vitamin B6 analogue is the first-line therapy for nausea and vomiting in pregnancy overseas. However, despite it being proven as the safest and most effective medicine it is not yet commercially available in Australia.

It is, however, available as a compounded preparation.

More information 

To learn more about the doxylamine/pyridoxine combination for managing nausea and vomiting in pregnancy, please contact one of our friendly pharmacists.


Vitamins in personal care products?

Custom personal care products… formulated exclusively for you.

Personal care products like moisturisers and shampoos are often quite complex mixtures of ingredients, but many commercial products seem to contain a bewildering and sometimes seemingly random array of ingredients that not everyone should want or need.

Everyone’s skin and hair is as different as their DNA… so why shouldn’t you choose what ingredients care for them best?

Different vitamins impart different properties upon a personal care product, determined by their chemistry and biological function. These characteristics make them particularly suitable for certain uses. Many beneficial actions have been described in scientific studies, as summarised below.

Vitamin C Potent antioxidant
Reduces damage & hyperpigmentation from sun exposure
Reduces the appearance of skin wrinkles & age spots
Vitamin A Improves skin cell turnover
Stimulates new blood vessel formation
Promotes collagen remodelling
Reduces the visible signs of ageing
May reduce acne
Vitamin B3 Important for cellular metabolism
Essential for healthy skin
May reduce acne, rosacea & skin hyperpigmentation
Reduces the visible signs of ageing
Vitamin E Strong antioxidant
Protects skin cell membranes from damage
May assist with wound healing
Vitamin B5 Increases skin elasticity
Nurtures skin against itching, dryness, and irritation
Improves the appearance of age-related skin changes like wrinkles & spots
May improve wound healing
May reduce the visibility of old and new scars
Vitamin K Reduces dark circles under eyes
Assists with bruise healing
May reduce rosacea
Vitamin B12 Necessary for metabolism of fatty & amino acids
Important in DNA synthesis
May relieve eczema & psoriasis
Coenzyme Q10 Potent antioxidant
Heals & repairs
Increases collagen production
May protect against damage from sun exposure
Reduces the appearance of skin wrinkles & age spots

Many of these vitamins are not generally available in commercial products, but we stock them all. Several vitamins with different properties can be combined into a single product, and they may be combined with other ingredients (e.g. natural oils) to enhance their characteristics. Any ingredient can be sourced and incorporated as required.

We have the expertise to prepare your personal care product in the way you wish it could be!
BCP products are unique, because they are formulated by pharmacists.

Contact us today to learn more and order your personalised product.

If you are looking for a custom-made moisturiser, consider our BCP Custom Skincare range: an easy 4-step approach to personalised skincare. Download your order form today!


The oils in our skincare products

Our BCP custom skincare… formulated exclusively for you.

Moisturisers (or emollients) are complex mixtures of ingredients. They work by increasing the skin’s hydration (water content) by decreasing the evaporation of water and by trapping it in the skin. Moisturisers are not one-size-fits-all. Everyone’s skin is as different as their DNA, and it is possible to select the best oil for your skin. One of the key factors that determines how well a moisturiser will work is the kind of oils that it contains.

Different oils have different properties, depending on their chemistry. Many commercial moisturisers contain low-quality petroleum-derived oils that can leave your skin feeling greasy or with blocked pores. Naturally-sourced oils may also contain vitamins or antioxidants that impart unique qualities into the oil. The overall character of each oil may make it suitable or unsuitable for some skin types and applications.

These are some of our preferred natural oils, and a summary of their beneficial properties (as described in the scientific literature):

Almond Oil High levels of omega 6 & 9 fatty acids
Moisturises all skin types
Squalene Sourced from olive oil
Natural component of human sebum
Extremely light & non greasy
May exert anti-tumor activity
Rosehip Oil Rich in omega 3, 6 & 9 fatty acids and Vitamins A, E & C
Rich in lycopene & beta carotene
Powerful antioxidant properties
Nurtures skin regeneration
Improves the appearance of age-related skin changes (e.g. wrinkles & spots)
Shea Butter Rich in omega 3, 6 & 9 fatty acids
Rich in vitamins E & A
Rich in polyphenol antioxidants
Anti-inflammatory, high emollience
Improves the appearance of age-related skin changes (e.g. wrinkles & spots)
Avocado Oil Contains omega 3, 6 & 9 fatty acids
Rich in Vitamins A & D
Soothes dry skin
May relieve eczema & psoriasis
Beeswax Anti-inflammatory
Contains vitamin A
Anti-bacterial properties
Good for very dry skin & nappy rash
Olive Oil High levels of omega 3 & 6 fatty acids
Suited to dry or mature skin
Soothes irritated skin
Lanolin oil Similar to the skin’s natural oils
High in moisturising alpha hydroxyl acids (AHA)
Very good for barrier creams
Coconut oil Antibacterial properties
Protects skin cells from damage
Deeply hydrating

We stock a range of high-quality organic oils, and specialty ingredients can be sourced as required. Oils with different properties can be combined into a single product, and may be combined with other ingredients (e.g. vitamins) to enhance their characteristics.

However you prefer your skincare, we have the expertise to give advice and prepare it—just for you!
Our BCP products are unique, because they are formulated by pharmacists.

Contact us today to learn more, or to have your personalised product formulated.

If you are looking for a custom-made moisturiser, consider our BCP Custom Skincare range: an easy 4-step approach to personalised skincare. Download your order form today!


Personalised skin and hair care

Do you have ultra-sensitive skin? Do skin care products just not seem to work for you?

Your skin

Everyone’s skin is different, as unique as your DNA. Many ingredients in commercially-available skin and hair care products can be irritating or simply inappropriate for some skin types, leaving your skin dry, oily, clogged, scaly — or even inflamed. Sadly, not all products are formulated well, and some use cheap ingredients.

Alternatively, you might simply wish that your hair or skin care product was better, somehow.

Your skin requires particular attention to what is used in its care.

Our personalised skin and hair care

Here at Border Compounding Pharmacy, we have the knowledge and experience to diagnose skin care problems and formulate products that are more suitable to your needs.

Airless-bottlesWe regularly formulate:

  • Creams and moisturisers
  • Soaps and cleansers
  • Shampoos and conditioners

Some examples of what we can do:

We use only highest-grade materials in our preparations, and our formulating pharmacists are industrially qualified.

Interested?

BCP products are unique, because they are formulated by pharmacists.

Contact us today with your needs. We are happy to spend time with you, discovering how we can help.

If you are looking for a custom-made moisturiser, consider our BCP Custom Skincare range: an easy 4-step approach to personalised skincare. Download your order form today!


Omeprazole for infant reflux and colic

Baby cryingWhat is colic?

Colic is defined as a regular periods of intense crying from an otherwise healthy and well-fed baby. Most often, the crying has no apparent cause. Colic does not typically result in any long-term problems, and most colicky babies will grow out of the condition between four months and one year of age.

Babies cry for many different reasons, and the diagnosis of colic must exclude all other potential causes of crying. When a baby’s colic has been diagnosed as caused by stomach acid reflux (also known as GORD, see below), a doctor may prescribe a liquid omeprazole formulation.

What is omeprazole?

Omeprazole belongs to a class of medications called proton pump inhibitors (PPIs). The main action of PPIs is a pronounced and long-lasting reduction of gastric (stomach) acid production. They are the most potent inhibitors of acid secretion available.

The maximum effectiveness of omeprazole occurs around two hours after administration, lasting for up to three days. However, stomach pain from certain conditions may not ease for several days. If symptoms persist, a doctor should be consulted.

Omeprazole

Omeprazole

What is omeprazole used for?

Omeprazole is used in the treatment of conditions where there is too much acid in the stomach. Gastro-oesophageal reflux disease (GORD) is the most common of these, in which stomach acid leaks upward into the oesophagus causing irritation and heartburn, a painful burning feeling in the chest or throat. In babies, GORD is sometimes a cause of colic.

In  adults, omeprazole is also used to treat peptic ulcers (sores that develop in the stomach or small intestine lining due to damage from stomach acid), oesophagitis (tissue damage to the lining of the oesophagus due to inflammation or irritation over a prolonged period), and Zollinger-Ellison syndrome (a rare disorder resulting in excessive production of stomach acid and often, multiple peptic ulcers).

Does omeprazole have any side effects?

Omeprazole has been used safely in both adults and children for a long time, and adverse effects are rare, even after long-term treatment.

Some very uncommon effects reported in adults include headache, nausea, diarrhea, abdominal pain, fatigue, and dizziness. Very rarely, babies treated with omeprazole may experience changes to their bowel habits (diarrhoea or constipation), vomiting, or a skin rash.

Liquid omeprazole formulations for infants

Unfortunately, the commercially-available infant liquid omeprazole formulations contain bicarbonate, which not only tastes unpleasant (making it difficult to administer to an unhappy baby) but bicarbonate may react with acid in the baby’s stomach to cause gas and bloating—thereby exacerbating colic problems.

However, it is possible to formulate an omeprazole suspension that contains no bicarbonate. Pleasant in flavour and not causing bloat, such suspensions are ideal for use with infants.

More information 

To learn more about pleasant-tasting infant formulations, please contact us.


Compounding of veterinary medicines

dog-cute

At Border Compounding Pharmacy, we work closely with local veterinarians to formulate a wide range of veterinary medicines.

We stock an array of dosage forms and veterinary flavourings to aid you in giving your pet or animal the medicine they need.

Some of the veterinary compounding services we provide include:

  • Human medicines re-formulated into doses suitable for animals.
  • Veterinary-only medicines.
  • Custom dosing of medicines to suit your pet’s body size.
  • Suspensions and liquids made from medicines only available as capsules and tablets —especially useful for animals that cannot be given tablets.
  • Flavourings to suit your pet’s palate (e.g. beef, chicken, or tuna).
  • Formulation of medicines into dog chews.
  • Transdermal medicines for cats in an easy-to-use click pen cream applicator. Such creams are most commonly applied to the ear.

We compound medicines for all types of animals. If you require a medicine compounded for your pet or animal, please contact us.


Customising medications and personal care products

Mortar-and-Pestle

Commercially available products cannot suit everybody.

A medicine’s dose form might be wrong to deliver the drug to the right place, or a patient might be physically unable to swallow a tablet or capsule. Some oral medications do contain excipients like gluten, lactose, colourings, flavourings or preservatives that are unsuitable for some people.

In other medications and personal care products such as moisturisers, shampoos, conditioners, cosmetics and deodorants, particular emulsifiers, preservatives, fragrances and various other ‘actives’ might force people to stop using them—even when they like a product or are receiving some benefit from it.

Alternatively, perhaps a product could do a little more… perhaps to assist in its delivery, or perhaps to improve it in some way. A little tweak might mean that one product could replace two…

At Border Compounding Pharmacy, we offer an extensive formulation and reformulation service. We can help you identify potential problems you may be having with certain ingredients of a product and re-design it without the offending chemical. We can “reverse-engineer” a product that you like, to enhance or change its properties. We can also add active or aesthetic ingredients to your specification.

We have helped people who have asked for:

…just to name a few examples!

Compounding is a creative endeavour, and we relish the opportunity to help you! Just contact our professional staff with your requirements.


Drug shortages and discontinuations

Out-of-stock

Having trouble obtaining your regular medications?

Border Compounding Pharmacy can help you continue with your medications during times of drug shortage or discontinuation, rather than requiring you to change your medications completely. We are currently compounding products to help with the increasing number of Australian drug shortages and discontinuations.

We strive to formulate replacements that are as close to the original product as possible.

Recently we have formulated replacements for:

If you require a medication that you cannot obtain,  please contact us.